Has there been an animal in history that had evolved to eat specifically humans?: Dinofelis, a jaguar-sized, powerful sabretoothed cat, was widespread in Africa, Asia and Europe from 8 million to 1.2 million years ago.
It had a mouth which was just the right size and shape to crush a medium-sized hominid skull:
It probably didn’t prey only on early humans, though. It would have eaten proto-chimps in Africa and gibbons in Asia, monkeys in both, and small to medium-sized game of all sorts.